"This content is an excerpt from the 'Health Topic' section of the 33rd HF Live Review*."
(Note: The video may have abrupt starts or ends.)
*HF Live Review: A live streaming session for patients participating in the BM Metabolic Transition Program at BM Korean Internal Medicine Clinic.
Insulin Resistance
A state of decreased physiological response to normal or high levels of insulin.
"A Crucial Mechanism in the Development of Metabolic Syndrome"
Insulin resistance refers to a condition where the body's tissues show a diminished physiological response to normal or even high levels of insulin. It is a primary driver behind the development of metabolic syndrome.
Symptoms such as chronic fatigue, frequent hunger, weight gain, cravings for sugar, post-meal drowsiness (food coma), and chronic, recurring muscle or joint pain are often closely linked to insulin resistance.
Dysfunction in insulin signaling leads to a domino effect: hormonal imbalances, increased estrogen, hypothyroidism, Polycystic Ovary Syndrome (PCOS), adult acne, eczema, and increased body fat. This can further escalate into a vicious cycle of abdominal obesity and dyslipidemia.
At BM Korean Internal Medicine Clinic, we see many patients suffering from these symptoms. To find the true cause, we must shift our perspective: it is often not a "lack" of insulin, but rather a history of "excessive exposure" to it that triggers these issues.
<References>
Wilcox G. Insulin and insulin resistance. Clin Biochem Rev. The Australian Association of Clinical Biochemists; 2005 May;26(2):19–39.
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